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. Author manuscript; available in PMC: 2012 May 12.
Published in final edited form as: J Med Chem. 2011 Apr 19;54(9):3260–3267. doi: 10.1021/jm101554k

Table 3.

Property summary of compound leads

Hit Molecular
Weight
Solubilitya
(μg/mL)
Solubility
(μM)
9 377.436 1.4 3.6
10 305.370 1.1 3.5
14 478.606 0.9 1.9
15 349.426 19.1 54.7
27 451.313 1.4 3.2
a

Solubility of compound in PBS was determined by measuring the chemiluminescence of total nitrogen contents (www.aniliza.com).