Table 2.
Summary of strain-transcendent Rifins found in at least three out of 3D7, HB3, Dd2 and IT
| 3D7 | HB3 | Dd2 | IT | Pairwise alignment score1 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gene ID | Found in F.I.2 | Gene ID | Gene ID | Gene ID |
3D7- HB3 |
3D7- Dd2 |
HB3- Dd2 |
IT- 3D7 |
IT- HB3 |
IT- Dd2 |
| RifA2_PFD0070c | HB3rifA2_025 | Dd2rifA2_p1263 | IT4rifA2_125 | 92 | 83 | 85 | ||||
| / | HB3rifB1_050 | Dd2rifB1_027 | IT4rifB_114 | 100 | 100 | 100 | ||||
| RifB_MAL13P1.495 | HB3rifB_t0224 | Dd2rifB_t038 | IT4rifB_111 | 94 | 94 | 99 | 100 | 99 | 100 | |
| RifB_PFE1630w | yes | HB3rifB_079 | Dd2rifB_081 | / | 99 | 85 | 87 | |||
| RifA_PFL2585c | yes | HB3rifA_098 | IT4rifA_031 | 99 | 96 | 99 | ||||
| RifA_PFD0645w | / | Dd2rifA_086 | IT4rifA_021 | 98 | 94 | 95 | ||||
| RifA_p_PFD1020c | yes | HB3rifA_p112 | / | IT4rifA_050 | 97 | 90 | 98 | |||
| / | yes | HB3rifA_051 | Dd2rifA_p100 | IT4rifA_052 | 99 | 100 | 98 | |||
| RifB_p_PFA0710c | yes | HB3rifB_p116 | Dd2rifB_p111 | IT4rifB_104 | 97 | 98 | 99 | 98 | 99 | 98 |
| RifA_PFE1635w | yes | HB3rifA_p115 | Dd2rifA_p107 | IT4rifA_p084 | 98 | 94 | 95 | 86 | 86 | 92 |
| RifA_p_t_PFD0134c | HB3rifA_p101 | / | IT4rifA_t072 | 100 | 95 | 90 | ||||
| RifA_p_PF11_0022 | / | Dd2rifA_p112 | IT4rifA_p087 | 98 | 86 | 87 | ||||
| RifA_p_MAL7P1.52 | / | Dd2rifA_p098 | IT4rifA_p088 | 91 | 97 | 96 | ||||
1Rifins with >90% amino acid identity between at least one pair of strains plus >80% amino acid identity between at least 2 other pairs of strains are shown.
2F.I: Brazilian field isolates [45]
3p=pseudogene: one or more stop codons or frameshifts within the sequence.
4t=truncated gene:part of the gene sequence is missing, possibly due to incomplete sequencing.