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Model to determine the impact of maternal immunity on development of allergic airway disease in offspring. Imm, Immunization (OVA-CFA, OVA-Al(OH)3 or BSA-CFA); Aer, challenge with aerosolized Ag (always matched to immunizing Ag). Parameters of OVA-induced allergic airway disease severity assessed in offspring were OVA-specific Ig levels in serum and composition of leukocytes in the airways.
