Table 2.
Extracellular nanoparticle transport studies using particle tracking.
| Author (year) | Vector | Diameter (nm) | Label | ECM | Microscope | Tracking software | Transport parameters | Ref. |
|---|---|---|---|---|---|---|---|---|
| Lai et al. (2007) | PEG-COOH-PS | 100–500 | Proprietary dye | CVM | EF | MetaMorph | MSD, D | [28] |
| Wang et al. (2008) | PEG-COOH-PS | 200 | AF 647-PS | CVM | EF | MetaMorph | MSD, D | [30] |
| Tang et al. (2009) | PSA, PSA-PEG, PLGA | 100–200 | Dox/PSA, PLGA | CVM, CFS | EF | MetaMorph, MATLAB | MSD | [32] |
| Lai et al. (2009) | PEG-COOH-PS | 100, 200, 500, 1000 | Proprietary dye | CVM | EF | MetaMorph | MSD | [34] |
| Lai et al. (2010) | PEG-COOH-PS, HSV-1 | 100–1000, 180 | Proprietary dye-PS AF488-HSV GFP-HSV |
CVM | EF | MetaMorph | MSD, D | [35] |
| Dawson et al. (2003) | COOH-PS APS |
100–500 | Proprietary dye | CFS | EF, confocal | MetaMorph | MSD, D | [29] |
| Suk et al. (2009) | COOH-PS | 100, 200, 500 | Proprietary dye | CFS | EF | MetaMorph | MSD, D | [36] |
| Dawson et al. (2004) | PLGA-DDAB COOH-PS |
<200 | Proprietary dye | PGM | Confocal | MetaMorph | MSD, D | [33] |
| Cu and Saltzman (2009) | PEG-PLGA | 170 | Coumarin 6 | CM | Fluorescence | ImageJ | D | [31] |
| Kawai et al. (2009) | QD705, fluosphere | 20, 40, 100 | Intrinsic | Interstitium | EF | Unspecified | MSD, D, v | [1] |
APS: Amine-modified polystyrene; CFS: Cystic fibrosis sputum; CM: Cervical mucus; CVM: Cervicovaginal mucus; D: Diffusion coefficient; Dox: Doxorubicin; ECM: Extracellular matrix; EF: Epifluorescence; GFP: Green fluorescent protein; HSV: Herpes simplex virus; MSD: Mean square displacement; PEG: Poly(ethylene glycol); PGM: Pig gastric mucus; PLGA: Poly(D,L-lactic-coglycolic) acid; PS: Polystyrene; PSA: Poly(sebacic acid); QD: Quantum dot; v: Velocity.