FIGURE 4. Delayed neurological deficits following TBI.
(A) Open-field activity testing was performed in sham-operated or TBI-induced mice at various time point following TBI. Activity, as measured by the average number of crosses per trial, was recorded. (B) Novel object recognition test of memory was performed in sham-operated or in mice at day 7 post-TBI, when PSD-95 expression was lowest. The average time spent exploring a novel object, a measure of recognition memory, was recorded and compared with sham-operated control mice. For all studies, n=6–8 mice/group and * was p<0.05 vs. sham.