Skip to main content
. 2011 Jul 13;31(28):10283–10292. doi: 10.1523/JNEUROSCI.1834-11.2011

Figure 1.

Figure 1.

Prolonged rebound firing is reduced by antagonizing group I mGluRs and does not require synaptic inhibition. A, Action potentials in a cerebellar nuclear cell, with a 500 ms, 100 Hz train of stimulation, before and after application of CPCCOEt. Fast excitatory input was blocked by DNQX and CPP. B, Summary of firing rate changes after stimulus trains with or without CPCCOEt. In this and all related figures, lines connect within-cell observations. Black symbols, Data from pups (P13–P15); gray symbols, data from weanlings (P22–P28). C, Action potentials recorded from another cell under the same conditions as in A, except inhibitory input was blocked by SR95531 (SR). D, Summary of the firing rate changes in SR95531 after stimulus trains with or without CPCCOEt. White symbols represent individual cells, and black symbols are mean ± SEM. In all figures, asterisks in all figures represent statistical significance (p < 0.05) for all comparisons by paired t tests; N.S., not significant; ctrl, control.