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. 2011 Jun 16;118(6):1653–1662. doi: 10.1182/blood-2010-11-316943

Figure 7.

Figure 7

Ribbon diagram of epitopes recognized by anti-Pg-RIBS mAbs. (A) Pg kringles 1-3 (PDB ID 1KIO, gray) showing mAb 51 binding residues Y154-K177 (red ribbon and bold characters). (B) Pg kringle 5 (PDB ID 5HPG, gray) showing mAb 109 binding residues H494-R504 (red ribbon and bold characters). (C) Pg protease domain (PBD ID 1L4D, gray) showing mAb 109 binding residues L652-K661 (red ribbon and bold characters). (D) Pg protease domain (PBD ID 1L4D, gray) showing mAb 116 binding residues V616-R637 (red ribbon and bold characters).