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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Lab Invest. 2010 Jun 14;90(12):1704–1717. doi: 10.1038/labinvest.2010.112

Figure 5.

Figure 5

Gclm null mice are resistant to MCD diet-induced fibrosis. Sirius red-stained section of MCD-fed liver of wt mouse (a) shows pericellular Sirius red staining (arrow), indicating collagen deposition; little staining is detected in MCD-fed Gclm (ko) null liver (b). Morphometric analysis of hepatic Sirius red staining (c). Staining was significantly increased in MCD-fed wt liver (wt MCD) compared with MCS-fed wt mice (wt MCS), and MCS or MCD-fed Gclm null mice (ko MCS; ko MCD). *P <0.05 compared with wt MCD, for all groups, n = 4–6 animals.