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. 2011 Aug 15;6(8):e23237. doi: 10.1371/journal.pone.0023237

Figure 4. Exposure after different dosing regimens of either 20 or 30 mg/kg ST-246 to cynomolgus monkeys.

Figure 4

The mean and standard deviation values for the plasma concentrations over time are shown for different dosing regimens of (A) 20 mg/kg or (B) 30 mg/kg. The dosing regimens included oral administration (3 males and 3 females in each dose group, green diamonds), 4 hour IV infusion (2 males and 2 females in each dose group, red circles), 6 hour IV infusion (2 males and 2 females in each dose group, blue diamonds), and BID two 4 hour IV infusions initiated 12 hours apart (4 males and 4 females in each dose group, black diamonds).