Table 3. Summary of the highest represented functional groups of genes from the differentially expressed gene list at E7.5.
| Category | Genes | Nb of genes |
| Proteolysis | Prss28,Prss29,Napsa,Mmp7,XM_001477507.1(similar to ISP-2),Ctsk,Ctso | 7 |
| Protease inhibition | Slpi,Cst9,A2m,Serpina1e | 4 |
| Biological adhesion | Igfbp7,Angpt2,Smoc2,Epdr1,Sned1,Igsf11,Nrcam,Lsamp,Thy1,Adam12,Cd36, Cd34,Lamb2,Gpnmb,Tdgf1,Fbln2,Msln,Lyve1,Cldn1,Cldn5 | 20 |
| Nervous system development | Igf1,Fgf5,Bdnf,Apob,Aqp1,Sgk1,Bmp2,Atoh8,Tgfbr2,Cldn5,Cldn1,Gja1,Thy1, Eomes,Ednrb,Mt3,Tacc1,Hoxd10,Hdac9,Nrcam,Corin,Mal,Lamb2 | 23 |
| Apoptosis | Tnfrsf11b,Igf1,Bdnf,Ednrb,Bmp2,Irak3,Tlr4,Pglyrp1,Pmaip1,Casp12,Tnfaip3, Gja1,Sgk1,Wt1,Srgn,Acvr1c,Anxa1,Cryab,Cryaa,Mal | 20 |
| Cell proliferation | Fgf5,Igf1,Bdnf,Ednrb,Lgr4,Tgfbr2,Tlr4,Ptges,Acvr1c,Fosl2;Bmp2 Ptgs1,Gja1,Mmp7,Nampt,Sat1,Anxa1,Pmaip1,Tdgf1,Tacc1 | 20 |
| Inflammatory and innate immune response | Tlr4,Serping1,Cd55,Bmp2,Tlr3,Lbp,Alox5,Ggt5,Anxa1,Hdac9,Cd36,Pglyrp1,Irak3 | 13 |
| Heart formation and blood vessel development | Apob,Cd36,Igf1,Wt1,Angpt2,Tgfbr2,Gja1,Tdgf1,Thy1,Cdx4,Tnfaip2 | 11 |
| Vascular diseases | Atp8b1,Ugt1a1,Slco1a6,Rgs5,Tnfaip2,Rgs2,Nrcam,Pmaip1,Lsamp,Pou5f1,Mixl, Tdgf1,Casp12,Lbp,Havcr2,Tlr4,Irak3,Tlr3,Fstl1,Add3,Ptn,Fgf5,Penk,Mt3,Bdnf, Tgfbr2,Fbln2,Fbn1,Mfap5,Col5a2,Dcn,Lum,Ramp3,Sparcl1,Timp3,Ednrb,Gpx3, Adam12,Abp1,Mgp,Bmp2,Fosl2,Vsig2,Cyp11b1,Igfbp7,Nampt,Sat1,Angpt2,Slpi, Igf1,Alox5,Anxa1,S100a4,Pglyrp1,Ptgs1,Ptges,Tnfaip3,Hdac9,Hsd11b1,Slc2a12,Srgn, Apob,Vldlr,Cd36,Tnfrsf11b,Ctsk,Cxcl14,Sgk1,Srd5a1,Bche,Gda,Abat,A2m,Gja1,Des,Dtna, Cryab,Cd34,Il6ra,Abcd1,Hoxa10,Sfrp4,Sfrp5,Dkk2,Wt1,Tacc1,Cldn1,Cldn10a,Cldn5, Lyve1,Emcn,Thy1,Cd55,Aqp1,Serping1,Ly6a,Ly6c1,Ly6c2,Gpihbp1 | 99 |
| Response to oxidative stress | Gpx3,Tlr4,Ptgs1,Anxa1,Cryab,Cryaa | 6 |
| Matrix metalloproteinase | Angpt2,Slpi,Igf1,Timp3,Tlr4,Rgs2,Irak3,Ptges,Alox5,S100a4,Adam12,Mmp7, Aqp1,Nampt,Wt1,Hoxa11,Bmp2,Tgfbr2,Bdnf,Fosl2,Jam2,Cldn5,Tnfrsf11b | 23 |
| Prion disease | Bdnf,Igf1,Dcn,Bche,Tgfbr2,Srgn,Aqp1,Cd34,Thy1,Ly6a,Cryab,Anxa1,Ptgs1, Alox5,Tlr3,Tlr4,Casp12,Mt3 | 18 |
UP-regulated genes are in bold type.