Fig. 6.

Characterization of core-shell nanoparticles. (A) Dried FF110 nanoparticles on mica showed uniform particle size around 34 nm by AFM. (B) TEM was utilized to visualize the core-shell structure of R126 nanoparticles. The insert clearly showed an electron dense cross-linked core, and a more electron loose shell. These TEM images are unstained. Additional AFM and TEM images appear in Fig. S3. Cell internalization of FITC-C80 (C) and FITC-C227 (D) nanoparticles after 1 hr of incubation was demonstrated by confocal microscopy. Punctate green fluorescence was observed within the cell.