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. 2011 Jul 26;108(32):13353–13358. doi: 10.1073/pnas.1103105108

Fig. 4.

Fig. 4.

Correlation of coassociated factors with NFκB binding. NFκB binding ratios (signal to background) can be predicted by fitting linear models of combinations of the control factors (A) and the “full” model (the control factors combined with four coassociated factors, EBF, STAT1, E2A, IRF2) (B). Although all signals are expected to be correlated because of open chromatin regions, a model fit using the coassociated factors (STAT1, EBF, E2A, and IRF2; r = 0.703) (B) is significantly more predictive of NFκB binding than one fit using the negative controls (ZNF143 and CTCF; r = 0.444) (A).