Table 1.
Summary of patient characteristics and HSP-70 results
RF ablation patient group | Liver biopsy patient group | |||
---|---|---|---|---|
Patients | n = 22 | Patients | n = 20 | |
Male | n = 16 | Male | n = 13 | |
Female | n = 6 | Female | n = 7 | |
Mean agea | 63 years (range: 28–81 years) | p = 0.002 | Mean agea | 50 years (range: 20–70 years) |
RF ablations | n = 32 (1–3 sessions per patient) | |||
1 session | n = 13 | |||
2 sessions | n = 8 | |||
3 sessions | n = 1 | |||
Treated organ | Biopsy organ | |||
Liver | n = 18 | Liver | n = 20 | |
Kidney | n = 2 | |||
Lung | n = 1 | |||
Lung and liver | n = 1 | |||
Primary diagnosisb | Primary diagnosisb | |||
CRC | n = 12 | Chronic viral hepatitis | n = 6 | |
HCC | n = 4 | HCC | n = 6 | |
RCC | n = 2 | Hepatic metastases | n = 2 | |
CCC | n = 1 | PBC | n = 2 | |
NCP | n = 1 | PSC | n = 1 | |
AGC | n = 1 | Steatohepatitis | n = 1 | |
CM | n = 1 | Ethylic liver cirrhosis | n = 1 | |
Graft rejection after LTX | n = 1 | |||
HSP-70 | HSP-70 | |||
Mean HSP-70 serum pre-RF (day 0) | 4.6 ng/ml | Mean HSP-70 serum pre-biopsy (day 0) | <1.0 ng/ml | |
SD 3.0 | ||||
Mean HSP-70 serum post-RF (day 1) | 7.3 ng/ml | p = 0.001 | Mean HSP-70 serum post-biopsy (day 1) | <1.0 ng/ml |
SD 4.6 | ||||
Mean HSP-70 serum first follow-up post-RF | 3.4 ng/ml | p = 0.004 | ||
SD 2.0 |
aAge at first RF ablation or at biopsy
bCRC colorectal carcinoma, HCC hepatocellular carcinoma, RCC renal cell carcinoma, CCC cholangiocellular carcinoma, NCP neuroendocrineous carcinoma of the pancreas, AGC adrenal gland carcinoma, CM choroidal melanoma, PSC primary sclerosing cholangitis, PBC primary biliary cirrhosis, LTX liver transplantation