Figure 1. GPR56 inhibits angiogenesis in melanomas.
A. Expression of GPR56 resulted in reduction in angiogenesis. Tumor sections from melanoma cells expressing wild-type GPR56 or vector control were stained with anti-GPRC antibody (red) and anti-PECAM antibody (green).
B. Quantification of blood vessel density in GPR56-expressing tumors and vector control.
C. Quantifications of blood vessel density in areas of the same GPR56-expressing tumors.