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. Author manuscript; available in PMC: 2012 Aug 26.
Published in final edited form as: Vaccine. 2011 Jun 23;29(37):6292–6300. doi: 10.1016/j.vaccine.2011.06.027

Figure 2.

Figure 2

Evaluation of S. mutans adherence to SAG in the presence of sera from immunized mice. Immunogens are indicated on the X-axis. BIAcore SPR analysis was used to evaluate bacterial adherence following incubation of S. mutans with sera collected from BALB/c mice immunized with PBS, S. mutans, or with immune complexes (IC) containing S. mutans and the Guy’s 13 plantibody at the indicated dilutions. For ease of presentation the changes in resonance units (ΔRU) detected over the entire 60 second injection cycle, rather than the sensograms, are shown. The assay was performed in triplicate and is representative of 4 separate SPR assays. Statistically significant differences between S. mutans and IC-immunized groups were evaluated by one-way analysis of variance (ANOVA) using Graph Pad Prism 4.0 *(p≤0.05)