Fig. 2.
Hierarchical clustering of thyroid samples including normal thyroid tissue (NL), follicular adenomas (FAs), and follicular carcinomas (FCs) by 1181 genes. Branches are designated A to G. The 2 major divisions are (A) comprised of all FCs and 1 FA, and (B) comprised of all NL and 3 of the 4 FAs. Subdivisions within branch (B) are (F) 10 of 11 NL samples further clustered tightly at the bottom adjacent to (E), 3 FAs and the remaining NL. FCs with metastases (FC-A; indicated in red) clustered in 2 regions in subdivision (D) and within branch (C) in cluster (G) admixed with indolent FCs. Sample numbers correspond to the patient numbers in Table 1.