Table 1.
Clinical data and MR findings in the study population
| Number | Gestational age (weeks) | Presentation | Initial MRI | Follow-up MRI | Main pattern of injury | Unilateral parenchymal hemorrhage | Cystic evolution | Grade by Sie | Grade by Childs | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age at MRI (weeks) | Number of PWML | Number with signal loss in PWML on SWI (%) | Reduced diffusion | Age at MRI (weeks) | No. of PWML | Number with signal loss in PWML on SWI (%) | Reduced diffusion | ||||||||
| Full-term infants | |||||||||||||||
| 1 | 40 | Perinatal asphyxia | 41 | 3 | 0 (0) | Yes | WMD | No | No | 3 | 2 | ||||
| 2 | 38 | Complex cyanotic heart defect | 39 | 13 | 5 (38.5) | Yes | WMD | No | No | 4 | 2 | ||||
| 3 | 40 | Screening for thrombosis | 41 | 1 | 0 | No | WMD | No | No | 3 | 1 | ||||
| 4 | 41 | Cyanotic congenital heart defect | 41 | 9 | 0 (0) | Yes | WMD | No | No | 4 | 2 | ||||
| 5 | 37 | Hypertonia, areflexia | 37 | 5 | 1 (20.0) | No | WMD | No | No | 3 | 2 | ||||
| 6 | 38 | Meningitis | 40 | 55 | 34 (61.8) | No | WMD | No | No | 4 | 2 | ||||
| 7 | 40 | Hemorrhagic colitis | 42 | 152 | 80 (52.6) | Yes | WMD | No | No | 4 | 3 | ||||
| Preterm infants | |||||||||||||||
| 8 | 32 | Car accident of the mother | 33 | 49 | 31 (63.3) | Yes | 41 | 36 | 16 (44.4) | No | GMH-IVH | Yes | No | 4 | 3 |
| 9 | 31 | Abnormal WM on US | 31 | 12 | 12 (100) | Yes | 42 | 2 | 2 (100) | No | GMH-IVH | No | No | 4 | 2 |
| 10 | 30 | Congenital hydrocephalus | 36 | 5 | 5 (100) | No | 42 | 4 | 4 (100) | No | GMH-IVH | No | Yes | 4 | 4 |
| 11 | 31 | Posthemorrhagic ventricular dilatation | 40 | 22 | 13 (59.1) | No | GMH-IVH | No | No | 4 | 2 | ||||
| 12 | 29 | IVH, venous infarction | 30 | 1 | 1 (100) | No | GMH-IVH | Yes | No | 4 | 2 | ||||
| 13 | 33 | IVH, venous infarction | 42 | 1 | 1 (100) | No | GMH-IVH | Yes | No | 3 | 1 | ||||
| 14 | 25 | Gut perforation, sepsis | 31 | 21 | 14 (66.7) | Yes | GMH-IVH | No | No | 4 | 2 | ||||
| 15 | 33 | IVH, venous infarction | 33 | 41 | 36 (87.8) | Yes | 42 | 13 | 7 (54) | No | GMH-IVH | Yes | No | 4 | 3 |
| 16 | 33 | Perinatal asphyxia, anemia | 34 | 57 | 24 (42.1) | Yes | 46 | 17 | 7 (41) | No | GMH-IVH/WMD | No | Yes | 4 | 4 |
| 17 | 29 | Venous infarction, cysticPVL | 40 | 57 | 15 (26.3) | No | GMH-IVH/WMD | Yes | Yes | 4 | 4 | ||||
| 18 | 34 | IRDS grade II | 35 | 98 | 1 (1) | Yes | 42 | 76 | 0 (0) | No | WMD | No | No | 4 | 3 |
| 19 | 28 | imhomogeneous PVE | 31 | 22 | 9 (40.9) | Yes | 41 | 12 | 9 (75) | No | WMD | No | No | 4 | 2 |
| 20 | 31 | Abnormal WM on US | 33 | 12 | 1 (8.3) | Yes | WMD | No | No | 4 | 2 | ||||
| 21 | 31 | imhomogeneous PVE | 32 | 59 | 0 (0) | Yes | WMD | No | Yes | 4 | 4 | ||||
| 22 | 29 | Cystic PVL | 41 | 9 | 5 (55.6) | No | WMD | No | Yes | 4 | 4 | ||||
| 23 | 31 | Hemorrhagic cystic PVL | 32 | 163 | 133 (81.6) | Yes | WMD | No | Yes | 4 | 3 | ||||
| 24 | 32 | PVE | 43 | 1 | 0 (0) | No | WMD | No | No | 3 | 1 | ||||
PWML punctate white matter lesions, WM white matter, US ultrasonography, PVL periventricular leukomalacia, PVE periventricular echodensities, IVH intraventricular hemorrhage, GMH germinal matrix hemorrhage, WMD subtle to severe white matter damage