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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Pharmacol Biochem Behav. 2011 Jun 29;99(4):671–675. doi: 10.1016/j.pbb.2011.06.025

Figure 4. Comparison of naltrexone and 6β-naltrexol to precipitate withdrawal following 1, 3 and 6 days of morphine treatment.

Figure 4

The ED50’s (+ SE) for naltrexone (A) and 6β-naltrexol (B) to precipitate withdrawal jumping for 1, 3 or 6 days of morphine treatment. (C) Relative potency (+ SE) of 6β-naltrexol compared to naltrexone (6β-naltrexol ED50/naltrexone ED50) for 1, 3 or 6 days morphine treatment.

*significantly different (p < 0.05) from the ED50 of 1 day morphine treatment group.