Fig. 5.

Hierarchical orchestration of the Bcl-2 family members in Ntv-a/PDGF cells. a Effect of the folate or PDGFri treatment on the interaction existing between anti-apoptotic proteins, Bax, and BH3-only proteins by using immunoprecipitation method (IP). b Effect of BH3 peptides (akin the BH3 domain of BH3-only proteins, 1 μM) on the interaction existing between Bcl-xl and BH3-only proteins by using immunoprecipitation method (IP). c Effect of the folate, PDGFri, or Akti treatment on the phosphorylation level of Bad in Ntv-a/PDGF cells