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Response to sildenafil infusion without iNO. Seven infants were enrolled before the need for iNO. OI was improved by 1 hour (24.6±4.6 to 16.1±9.9; *P=0.0502), with significant and sustained improvement by 4 hours after the initiation of sildenafil (14.7±6.4, p=0.0088). From (91), with permission.
