Table 1.

Summary of the large, multicenter randomized trials of inhaled NO in term newborns with hypoxemic respiratory failure and/or PPHN, showing the effect of iNO on ECMO utilization and mortality. Table adapted from (85), * denotes significant reduction (p < 0.05).

			% ECMO		% Mortality
	n	Initial OI	Control	iNO	Control	iNO
NINOS (86)	235	44	55	39*	17	14
Roberts (87)	58	44.4	71	40*	7	7
Clark (88)	248	39	65	48*	8	7
Davidson (89)	155	24.7	34	22	2	8
Konduri (32)	299	19.2	12	10	9	7