Figure 5. ALRF completely abolishes selectin-mediated slow rolling.
(A + B) The carotid artery of control mice and mice with ALRF were cannulated with a catheter, which was connected to autoperfused flow chambers. (A) Average rolling velocity of neutrophils on P-selectin (left) and P-selectin/ICAM-1 (right) is presented as mean ± SEM (n=6–10). (B) Average rolling velocity of neutrophils on E-selectin (left) and E-selectin/ICAM-1 (right) is presented as mean ± SEM (n=6–10). The wall shear stress in all flow chamber experiments was 5–6 dynes/cm2. # p < 0.05.