Table 3.
Logistic Regression relating glucose metabolism with metabolic variables
| Exposure | Outcome | Multivariate1 | |
|---|---|---|---|
| Odds ratio | 95% CI | ||
| Fasting glucose (mmol/L) | Hypertension2 | 2.15 | (0.78 - 5.89) |
| 1-hr OGTT (mmol/L) | Hypertension | 1.25 | (1.00 - 1.56) |
| 2-hr OGTT (mmol/L) | Hypertension | 1.15 | (0.83 - 1.59) |
| Fasting insulin (pmol/L) | Hypertension | 1.02 | (1.00 - 1.03) |
| HOMA IR index | Hypertension | 1.48 | (1.06 - 2.06) |
| Fasting glucose (mmol/L) | Hypercholesterolemia3 | 1.22 | (0.46 -3.21) |
| 1-hr OGTT (mmol/L) | Hypercholesterolemia | 1.20 | (0.97 - 1.49) |
| 2-hr OGTT (mmol/L) | Hypercholesterolemia | 1.17 | (0.84 - 1.61) |
| Fasting insulin (pmol/L) | Hypercholesterolemia | 1.00 | (1.00 - 1.01) |
| HOMA IR index | Hypercholesterolemia | 1.09 | (0.89 - 1.35) |
| 1-hr OGTT(mmol/L) | Pre-diabetes4 | 1.75 | (1.28 - 2.39) |
| 2-hr OGTT (mmol/L) | Pre-diabetes | 3.97 | (2.03 - 7.78) |
| Fasting insulin (pmol/L) | Pre-diabetes | 1.02 | (1.01 - 1.03) |
| HOMA IR index | Pre-diabetes | 1.95 | (1.35 - 2.83) |
| Fasting glucose (mmol/L) | Metabolic syndrome5 | 4.62 | (1.62 - 13.2) |
| 1-hr OGTT (mmol/L) | Metabolic syndrome | 1.50 | (1.18 - 1.91) |
| 2-hr OGTT (mmol/L) | Metabolic syndrome | 1.48 | (1.06 - 2.05) |
| Fasting insulin (pmol/L) | Metabolic syndrome | 1.02 | (1.01 - 1.04) |
| HOMA IR index | Metabolic syndrome | 2.07 | (1.45 - 2.97) |
Adjusted for age, sex, smoking (never vs. ever) and physical activity (structured or vigorous)
Hypertension = Have systolic BP ≥130 or diastolic BP ≥ 85 mm Hg or self-report of high BP or self-report of taking medication for high BP
Hypercholesterolemia = Have total cholesterol ≥ 240mg/dL OR self-report of high cholesterol or self-report of taking medication for high cholesterol
Pre-diabetes = Have fasting plasma glucose (Impaired FPG) ≥ 100mg/dL or have 2hr-glucose tolerance test ≥ 140mg/dL (Impaired GT)
Metabolic syndrome = Have 3 out of 5 of the following criteria (ATPIII definition)
Abdominal obesity (waist circumference): men >102 cm; women > 88 cm
Triglycerides ≥ 150mg/dL
HDL Cholesterol: men < 40 mg/dL; women <50mg/dL
Hypertension = Have systolic BP ≥130 or diastolic BP ≥ 85 mm Hg or self-report of high
BP or self-report of taking medication for high BP
Fasting Plasma glucose ≥ 100mg/dL