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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Micron. 2011 Jun 25;42(8):762–772. doi: 10.1016/j.micron.2011.06.005

Figure 8. Structure analysis of the Notch extracellular domain (NECD) using a cryo-negatively stained Affinity Grid preparation.

Figure 8

The left panel shows a raw image with the white circles indicating individual particles. The scale bar is 25 nm. The right panels show 3D reconstructions of the NECD in three different conformations. Figure adapted from Kelly et al., 2010c.