Skip to main content
. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: Chem Res Toxicol. 2011 Jul 20;24(8):1327–1337. doi: 10.1021/tx200218u

Figure 5.

Figure 5

Time-dependent changes in the formation of resorufin by incubating 7-ethoxyresorufin with P450 1B1 in the absence (Control) and in the presence of 0.0083 µM, 0.033 µM, 0.083 µM, 0.33 µM, and 0.83 µM m-XSC in Figure 5A and in the presence of 0.083 µM o-XSC, 0.083 µM m-XSC, 0.083 µM p-XSC, and 0.083 µM BSC in Figure 5C. E. coli membranes expressing P450 1B1 and NADPH-P450 reductase were mixed with 7-ethoxyresorufin and chemical inhibitors, and the reactions were started by adding NADPH. The semi-logarithmic plots of the percent relative activity (activities with vs without inhibitors) are shown in different concentrations of m-XSC (B) and 0.083 µM each of o-, m-, and p-XSC and BSC (D).