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. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: Chem Res Toxicol. 2011 Jul 20;24(8):1327–1337. doi: 10.1021/tx200218u

Figure 6.

Figure 6

Effects of preincubation time on the inhibition of P450 1B1-dependnet EROD activities by m-XSC. E. coli membranes expressing P450 1B1 and NADPH-P450 reductase were first incubated without (Control) or with 0.033 µM, 0.083 µM, and 0.33 µM m-XSC in the presence of NADPH. 7-Ethoxyresorufin was added at incubation time of 0 min (A, without preincubation), 2 min (B, with preincubation for 2 min), and 4 min (C, with preincubation for 4 min) and the formation of resorufin was determined as a function of time.