Table 4.
Percentage bias (95% confidence interval) of eGFR calculated using the CKD-EPI equation and MDRD equation with mGFR by iothalamate renal clearance by age group
| Equation | Age Group | Potential Kidney Donors | Postnephrectomy Kidney Donors | Native CKD | Kidney Recipients | Other Organ Recipients |
|---|---|---|---|---|---|---|
| CKD-EPI | <40 years | −8% (−10%, −5%) | a | 18% (10%, 27%) | 12% (8%, 16%) | 14% (7%, 21%) |
| 40 to 69 years | −9% (−11%, −7%) | −9% (−13%, −5%) | 4% (1%, 6%) | 7% (5%, 8%) | 9% (6%, 12%) | |
| >70 years | a | a | 5% (2%, 8%) | 10% (5%, 14%) | 8% (1%, 14%) | |
| MDRD | <40 years | −19% (−22%, −17%) | a | 8% (0%, 16%) | 1% (−3%, 4%) | 2% (−5%, 8%) |
| 40 to 69 years | −17% (−19%, −16%) | −17% (−20%, −13%) | 0% (−2%, 2%) | 0% (−2%, 1%) | 3% (0%, 5%) | |
| >70 years | a | a | 9% (5%, 12%) | 11% (6%, 15%) | 8% (1%, 15%) |
The percentage bias was calculated as follows: {Σ [(eGFR − mGFR)/mGFR]}/n. CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease; eGFR, estimated GFR.
a
Group contained <10 persons to estimate bias.