Table 5.
Percentage bias (95% confidence interval) of eGFR calculated using the CKD-EPI equation and MDRD equation with mGFR by iothalamate renal clearance by gender
| Equation | Gender | <40 years old |
40 to 69 years old |
≥70 years old |
|||
|---|---|---|---|---|---|---|---|
| Before and after Kidney Donation | CKD and Transplant Recipients | Before and after Kidney Donation | CKD and Transplant Recipients | Before and after Kidney Donation | CKD and Transplant Recipients | ||
| CKD-EPI | Male | −6.9% (−10.6%, −3.2%) | 19.2% (13.2%, 25.3%) | −9.5% (−11.8%, −7.3%) | 6.7% (4.8%, 8.7%) | a | 7.4% (4.0%, 10.7%) |
| Female | −7.2% (−10.6%, −3.9%) | 11.0% (4.5%, 17.6%) | −8.6% (−10.6%, −6.7%) | 5.4% (3.7%, 7.1%) | a | 4.4% (1.2%, 7.4%) | |
| MDRD | Male | −17.8% (−21.4%,−14.2%) | 8.9% (3.3%, 14.5%) | −16.3% (−18.5%, −15.8%) | 1.0% (−0.7%, 2.6%) | a | 11.5% (7.9%, 15.0%) |
| Female | −19.6% (−22.8%, −16.4%) | −1.5% (−7.6%, 4.5%) | −17.6% (−19.5%, −15.8%) | −0.4% (−2.3%, 1.5%) | a | 5.3% (2.2%, 8.5%) | |
The percentage bias was calculated as follows: {Σ [(eGFR − mGFR)/mGFR × 100%]}/n. CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease; eGFR, estimated GFR; mGFR, measured GFR.
a
Group contained <10 persons to estimate bias.