Table 1.

NMR Data of 1 (DMSO-d₆) ^a

	No.	δC, mult.b	δH (J in Hz)	COSY	HMBC
	1	169.0, C
	2	71.8, CH2	3.81, d (2.0)		1, 3
	3	59.2, CH3	3.37, s		2
Hle	4-NH		7.43, d (8.8)	4	1, 9
	4	50.4, CH	5.50, dd (8.8, 8.8)	4-NH, 5	1, 5, 6, 9
	5	75.7, CH	3.43*	4, 5-OH, 6	4, 6, 7, 8, 9
	5-OH		4.79, d (7.1)	5
	6	29.8, CH	1.64, m	5, 7, 8	4, 5, 7, 8
	7	20.8, CH3	0.87, d (7.1)	6	5, 6, 8
	8	16.1, CH3	0.83, d (7.1)	6	5, 6, 7
	9	173.0, C
Pip	13-NH		4.50, br s	13	9
	10	51.5, CH	4.95, d (4.9)	11	9, 11, 12, 14
	11	26.5, CH2	2.09, m, 1.63, m	10, 12	10, 12, 13
	12	21.4, CH2	1.34, m	11, 13	10, 11, 13
	13	46.7, CH2	2.79*	12	11, 12
	14	171.0, C
Ahmppa	15-NH		7.59, d (8.0)
	15	53.3, CH	4.13, dd (8.0, 8.0)	15-NH, 16, 21	14, 16, 17, 21, 22
	16	38.3, CH2	2.79*	15	15, 17, 18, 21
	17	139.9, C
	18, 18′	129.8, CH	7.21, dd (7.4, 1.2)	19	16, 17, 19, 20
	19, 19′	128.8, CH	7.23, dd (7.4, 7.4)	18, 20	17, 18, 20
	20	126.6, CH	7.14, dd (7.4, 1.2)	19	18, 19
	21	72.4, CH	3.44*	15, 21-OH, 22	15, 22, 23, 24
	21-OH		5.08, d (7.1)	21
	22	43.7, CH	2.23, q (6.6)	21, 23	15, 21, 23, 24
	23	15.7, CH3	1.05, d (6.6)	22	21, 22, 24
	24	174.8, C
Auba	25-NH		8.10, q (10.3)	25	24, 28
	25	52.8, CH	4.38, dd (10.3, 8.1)	25-NH, 26	24, 26, 28
	26	23.9, CH2	2.15, q (10.3), 1.93, q(10.3)	25, 27	25, 27, 28
	27	42.1, CH2	3.71 dd (10.3, 10.3), 3.43*	26	25, 26, 28, 29
	28	175.2, C
	29	153.4, C
	29- NH2		7.40, br s, 7.74, br s

^a500 MHz for ¹H NMR and 75 MHz for ¹³C NMR.

^bNumbers of attached protons were determined by analysis of DEPT spectra.

^*The coupling constant was not determined because of overlapping signals.