Table 2.

NMR Data of 2 and 3 (DMSO-d₆)^a

	No.	2			3
		δC, mult.b	δH (J in Hz)		δC, mult.b	δH (J in Hz)
	1	168.3, C			169.0, C
	2	71.1, CH2	3.81, d (2.0)		71.1, CH2	3.81, d (2.0)
	3	58.6, CH3	3.37, s		58.5, CH3	3.32, s
Hle	4-NH		7.44, d (8.8)	Hle		7.48, d (8.4)
	4	49.9, CH	5.50, dd (8.8, 8.8)		50.0, CH	5.48, dd (8.4, 8.4)
	5	75.1, CH	3.43*		75.0, CH	3.40*
	5-OH		4.93, br s			4.84, br s
	6	29.2, CH	1.64, m		29.1, CH	1.64, m
	7	20.0, CH3	0.87, d (7.1)		20.1, CH3	0.88, d (6.8)
	8	15.5, CH3	0.83, d (7.1)		15.6, CH3	0.83, d (6.8)
	9	172.2, C			172.7, C
Pip	13- NH		4.50, br s	Pip		4.43, br s
	10	51.0, CH	4.95, d (4.9)		50.6, CH	4.95, d (4.9)
	11	25.9, CH2	2.09, m, 1.63, m		26.0, CH2	2.03, m, 1.63, m
	12	20.7, CH2	1.34, m		20.7, CH2	1.34, m, 1.15, m
	13	46.6, CH2	2.79*		46.0, CH2	2.79*
	14	170.2, C			170.5, C
Ahmppa	15-NH		7.66, d (8.0)	App		7.69, d (8.0)
	15	52.7, CH	4.13, dd (8.0, 8.0)		53.0, CH	4.03, dd (8.0, 8.0)
	16	37.9, CH2	2.79*		36.4, CH2	2.68, dd(14.0,6.5), 2.85, dd (14.0, 6.5)
	17	139.9, C			139.9, C
	18, 18′	129.1, CH	7.21, dd (7.4, 1.2)		129.1, CH	7.21, dd (7.4, 1.2)
	19, 19′	128.8, CH	7.23, dd (7.4, 7.4)		128.1, CH	7.23, dd (7.4, 7.4)
	20	126.6, CH	7.14, dd (7.4, 1.2)		126.6, CH	7.14, dd (7.4, 1.2)
	21	71.8, CH	3.44*	71.8, CH	3.21*
	21-OH		4.82, br s
	22	43.0, CH	2.23, q (6.6)	26.4, CH2	1.28, m
	23	14.9, CH3	1.05, d (6.6)	11.3, CH3	0.79, t (6.8)
	24	174.2, C
Aaba	25-NH		8.20, q (10.3)
	25	52.1, CH	4.38, dd (10.3, 8.1)
	26	23.2, CH2	2.15, q (10.3), 1.93, q (10.3)
	27	41.3, CH2	3.71 dd (10.3, 10.3), 3.43*
	28	173.3, C
	29	170.3, C
	30	25.5, CH3	2.37, s

^a500 MHz for ¹H NMR and 75 MHz for ¹³C NMR.

^bNumbers of attached protons were determined by analysis of 2D spectroscopic data.

^*The coupling constant was not determined because of overlapping signals.