Table 1.

Hematological and biochemical parameters were measured to assess physiological status of diabetic animals. Similarly to human diabetic patients, pigs with hyperglycemia also exhibit hyperlipidemia. Detailed statistical analysis in Material and Method section.

Substance	Initial (pre-STZ)	1 month	2 months	3 months	Reference values*
Glucose (mmol/l)	2.91 ± 0.16	22.76 ± 1.27	22.6 ± 1.27	24.01 ± 1.34	1.50–3.5
Hemoglobin (mmol/l)	6.79 ± 0.25	5.70 ± 0.19	5.74 ± 0.09	5.85 ± 0.13	5.5–10.4
BUN (mmol/l)	2.59 ± 0.42	5.96 ± 0.69	6.74 ± 6.74	6.19 ± 1.26	0.70–7.85
Creatinine (µmol/l)	53.04 ± 9.72	54.80 ± 3.27	67.18 ± 9.72	74.26 ± 13.23	106–180
GGT (U/l)	47.33 ± 6.5	61.16 ± 1.9	71.5 ± 13.56	69.5 ± 10.72	14–34
Cholesterol (mmol/l)	2.73 ± 0.14	6.35 ± 1.31	6.95 ± 1.54	8.96 ± 1.54	1.3–2.6
Triglyceride (mmol/l)	0.65 ± 0.14	1.19 ± 0.48	2.33 ± 0.88	2.85 ± 1.17	0.2–0.65
LDL (mmol/l)	1.56 ± 0.22	3.72 ± 1.12	4.47 ± 1.156	5.03 ± 1.11	0.6–2
HDLD (mmol/l)	0.87 ± 0.11	2.29 ± 0.13	2.37 ± 0.14	2.51 ± 0.03	0.6–2

^*Swindel M. Appendix. Hematology and Serum Chemistry. In: Swindel M, Swine in the laboratory: Surgery, Anaesthesia, Imaging and Experimental Techniques. 2nd ED, CRC Press; 2007:409 Bollen PJ. Hansen AK, Rasmusen HJ. Important Biological Features. Normative Values. In: The laboratory swine. CRC Press, 2000: 14. Winnicka A. Reference Values of common laboratory tests in veterinary medicine (In Polish). Warszawa, Poland. Wydawnictwo SGW. 1997 Holevet et al. Arterioscler Thromb Vasc Biol. 1998;18:415–22 (and references within).