Table 1.
Demographic and Clinical Characteristics of HIV-infected and Control Men
| Age-Restricted (33-45 years)* | All | ||||
|---|---|---|---|---|---|
| Control | HIV | P-value | HIV | ||
| n | 145 | 390 | 737 | ||
| Age (y) | Median (IQR) | 40.0 (38.0-43.0) | 40.0 (37.0-43.0) | 0.64 | 43.0 (38.0-49.0) |
| Race | Caucasian | 55% | 57% | 0.053** | 56% |
| African-American | 45% | 31% | 32% | ||
| Hispanic | 0 | 11% | 9% | ||
| Other | 0 | 1.5% | 2% | ||
| Physical Activity*** | 1st Quartile | 26% | 43% | 0.001 | 49% |
| 2nd Quartile | 26% | 17% | 20% | ||
| 3rd Quartile | 25% | 22% | 17% | ||
| 4th Quartile | 23% | 17% | 15% | ||
| Inadequate Food | 12% | 22% | 0.010 | 20% | |
| Current Smoker | 21% | 45% | <.0001 | 41% | |
| Alcohol | None | 15% | 24% | 0.013 | 25% |
| <1/week | 24% | 30% | 28% | ||
| 1-7/week | 37% | 31% | 31% | ||
| >7/week | 24% | 15% | 17% | ||
| BMI (kg/m2) | Median (IQR) | 26.9 (24.6-29.8) | 24.3 (22.3-26.6) | <.0001 | 24.3 (22.1-26.6) |
| VAT (L) | Median (IQR) | 2.0 (1.1-3.0) | 1.6 (0.68-2.7) | 0.006 | 1.7 (0.75-3.0) |
| Leg SAT (L) | Median (IQR) | 4.5 (3.7-5.7) | 2.9 (2.0-4.2) | <.0001 | 2.8 (2.0-4.0) |
| Lower Trunk SAT (L) | Median (IQR) | 5.6 (4.1-7.4) | 3.4 (2.0-5.3) | <.0001 | 3.3 (2.1-5.1) |
| Upper Trunk SAT (L) | Median (IQR) | 3.0 (2.3-4.16) | 2.5 (1.7-3.5) | <.0001 | 2.5 (1.7-3.6) |
| Arm SAT (L) | Median (IQR) | 1.1 (0.89-1.4) | 0.97 (0.78-1.4) | 0.018 | 0.97 (0.79-1.3) |
| Total Adipose Tissue (L) | Median (IQR) | 17.0 (12.9-21.5) | 11.9 (8.7-17.3) | <.0001 | 11.9 (8.8-17.1) |
P-value from Mann-Whitney test or Fisher’s Exact Test. Excluding all participants with recent opportunistic infections
HIV-infected participants are those restricted to the age range of controls.
: Race comparison is proportion of Caucasians vs. African-Americans
: First quartile of physical activity is least active, and fourth quartile is most active.
Note: Adipose tissue measures are height-normalized and back-transformed
Abbreviations: IQR = interquartile range; IDU = illicit drug use; MSM = men having sex with men.