Table 5.
Multivariable, linear regression analysis of HIV-related factors associated with lipid and lipoprotein levels in HIV+ Men*
| Triglycerides n=665 |
LDL n=637 |
HDL n=705 |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| % Effect | 95% CI | p-value | % Effect | 95% CI | p-value | % Effect | 95% CI | p-value | |
| Current CD4+ cell count (log2) | 8 | (2,15) | 0.014 | 6 | (3,10) | 0.001 | 1 | (−1,4) | 0.24 |
| Current HIV Viral Load (log10) | 0 | (−6,7) | >0.99 | −5 | (−9,−1) | 0.015 | −7 | (−9,−4) | <.0001 |
| AIDS Defining Illness by OI/CD4 | 24 | (8,42) | 0.002 | ||||||
| Currently on: Ritonavir | 52 | (34,73) | <.0001 | ||||||
| Currently on: Abacavir | 16 | (1,33) | 0.040 | ||||||
| Currently on: Nevirapine | 21 | (12,30) | <.0001 | ||||||
| Currently on: Efavirenz | 10 | (4,16) | 0.001 | ||||||
| Currently on: Indinavir | −7 | (−13,−1) | 0.025 | ||||||
*
NOT age-restricted
Note: Model also controls for demographic and lifestyle factors, and regional adipose tissue volumes
N differs for the different lipid and lipoprotein levels due to missing fasting lipid data