Table 1.
No AIDS Before HAART (N = 472) |
AIDS Before HAART (N = 124) |
Total (N = 596) | |||
No FRP* (N = 436) | FRP* (N = 36) | No FRP* (N = 77) | FRP* (N = 47) | ||
Date of HAART initiation† | 2/97 (7/96–1/98) | 10/96 (5/96–7/97) | 6/96 (2/96–1/97) | 7/96 (2/96–3/97) | 12/96 (5/96–11/97) |
Education higher than or equal to college, n (%) | 241 (56) | 16 (46) | 51 (66) | 29 (62) | 337 (57) |
Ethnicity = White non-Hispanic, n (%) | 365 (84) | 31 (86) | 66 (86) | 41 (87) | 503 (84) |
Age† | 43 (38–48) | 44 (40–49) | 43 (39–46) | 43 (39–46) | 43 (38–48) |
Maximum viral load (log10 copies/mL)*,† | 4.8 (4.3–5.2) | 5.2 (4.6–5.4)‡ | 5.3 (4.8–5.6) | 5.3 (5.0–5.7) | 5.0 (4.4–5.3) |
Nadir CD4+ cell count (per mm3)*,† | 271 (163–388) | 239 (86–393) | 116 (26–239) | 61 (15–170)‡ | 226 (125–359) |
Nadir Hgb before HAART (g/dL)*,† | 13.8 (13.1–14.5) | 13.2 (11.2–14.2)‡ | 12.7 (11.8–13.7) | 11.4 (10.0–13.1)‡ | 13.6 (12.5–14.3) |
Duration of HIV infection (y)†,§ | 11.6 (8.5–12.6) | 11.5 (8.6–12.0) | 11.5 (10.3–12.2) | 11.6 (10.6–12.1) | 11.6 (8.7–12.5) |
Among seroconverting men | 7.7 (5.4–11.4) | 8.5 (5.6–11.5) | 9.0 (7.1–10.9) | 9.0 (6.7–10.8) | 8.3 (5.6–11.3) |
Among seroprevalent men | 11.9 (11.0–12.8) | 11.8 (11.1–12.4) | 11.7 (11.3–12.4) | 11.8 (11.4–12.5) | 11.8 (11.2–12.7) |
HAART responders, n (%)‖ | 311 (77) | 24 (71) | 38 (58) | 24 (59) | 397 (73) |
Number of visits assessable for FRP*,† | 5 (4–6) | 4 (4–6) | 4 (3–5) | 4 (3–5) | 4 (4–6) |
>25% manifesting FRP visits, n (%)* | 0 | 18 (50) | 0 | 28 (60) | 46 (8) |
Notes: FRP = frailty-related phenotype; HAART = highly active antiretroviral therapy; Hgb, hemoglobin.
Within the 3 years before HAART.
Median (interquartile range).
p ≤ ·05 when comparing men with FRP with those without FRP at HAART initiation FRP.
Durations calculated from estimated date of seroconversion for seroconverting men (N = 178) and from first HIV-positive visit for seroprevalent men (N = 418).
Defined as a viral load of <1,000 copies/mL within 1 year after starting HAART, % are based on nonmissing data.