Table 3. GDT association results (P<0.05) for COME/ROM.

Chr	SNP	Position	Allele	Frequency	P	δ	OR	Genes
9	rs2770146	117552892	G	0.307	0.038	−0.062	0.736	TLR4
10	rs1051246	81687798	C	0.118	0.039	−0.058	0.499	SFTPD *
11	rs7396030	1073364	T	0.196	0.049	0.078	1.565	MUC2
11	rs2075859	1207064	T	0.374	0.041	−0.067	0.744	MUC5AC,MUC5B
11	rs2735733	1218216	T	0.461	0.002	−0.106	0.646	MUC5AC,MUC5B
19	rs8100085	40214959	A	0.313	0.013	−0.090	0.636	SCN1B

Note: Analyses are adjusted for sex and age at exam. δ is the allele frequency difference between affected and unaffected individuals. The odds ratio (OR) of association is converted from δ and MAF, assuming a population prevalence of 0.1.

*This SNP was selected due to its proximity to COME/ROM candidate gene SFTPD, but is located within the mannose-binding protein-A pseudogene (MBL1P1) gene.