Table 1. Tumorigenicity of tumor cell subpopulations in vivo.
| number of cells transferred | ||||||
| cell type | 1×106 | 1×105 | 1×104 | 1×103 | 5×102 | 2×102 |
| Unsorted cell | 8/8 | 6/9 | 2/9 | 0/9 | 0/9 | 0/9 |
| CD44hi | 7/7 | 9/9 | 8/8 | 7/9 | 3/9 | 0/9 |
| CD44neg | 8/8 | 5/9 | 1/8 | 0/9 | 0/9 | 0/9 |
| CD44hiCD133+CD117+ | 4/4 | 5/5 | 8/8 | 9/9 | 6/9 | 3/9 |
| CD44negCD133+CD117+ | 3/7 | 2/8 | 1/9 | 0/9 | 0/9 | |
Subpopulations of tumor cells were sorted with markers as indicated and transferred at indicated doses to wildtype mice recipients. Recipients were monitored up to 3 months after transfer for tumor formation. Unsorted tumor cells were used as control. (numbers in the table: tumor bearing mice/injected mice).