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Nissl-stained motor neuron count in the lumbar spinal cord. The effect of the PGC-1α on neuron numbers in SOD1-G93A transgenic mice at post-symptomatic stage (day 110) was examined following Nissl-staining. (A) Photomicrographs of representative Nissl-stained sections through the ventral horns of the lumbar spinal cord from wild-type (WT), SOD1-G93A, PGC-1α and SOD1-G93A/PGC-1α double transgenic mice. (B) Motor neuron counts in lumbar spinal cord (data = Mean ± SE, n = 5, **p < 0.05).
