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. Author manuscript; available in PMC: 2012 Aug 17.
Published in final edited form as: J Am Chem Soc. 2011 Jul 21;133(32):12406–12409. doi: 10.1021/ja204924j

Table 1.

Solvent Screening for Silanol-Directed Alkenylationa

graphic file with name nihms314283t1.jpg
entry solvent (0.1 M) conversion,%b yield, %c
1 C6F6 77 52
2 PhCF3 79 50
3 PhMe 43 24
4 dioxane 18 <3
5 THF 4 <3
6 t-AmylOH 26 <3
7 DCE 90 78
8 DMF 55 0
a

1a/2a = 1 : 2, L1 = (+)Menthyl(O2C)-Leu-OH.

b

Consumption of starting material 1a measured by GC/MS.

c

1H NMR yield.