Table 2. Comparison of EKC patients among pre-pandemic, pandemic and post-pandemic periods.

Age	Weeks*	Periods†			t-value of t-test between pre-pandemic & pandemic‡	t-value of t-test between pre & post-pandemic‡
		Pre-pandemic cases mean [CI]	Pandemic cases	Post-pandemic cases
Total age	Total	54711 [45282–64140]	30159	61845	t value = −7.23 (p = 0.002)	t value = 2.10 (p = 0.104)
	Epidemic	36608 [27092–46124]	17188	43095	t value = −5.67 (p = 0.005)	t value = 1.89 (p = 0.131)
	Non-epidemic	18103 [15415–20791]	12971	18750	t value = −5.30 (p = 0.006)	t value = 0.67 (p = 0.541)
0–9yr	Total	9357 [7667–11047]	5558	12689	t value = −6.24 (p = 0.003)	t value = 5.47 (p = 0.005)
	Epidemic	6223 [4859–7588]	3243	9173	t value = −6.06 (p = 0.004)	t value = 6.02 (p = 0.004)
	Non-epidemic	3134 [2590–3678]	2315	3516	t value = −4.18 (p = 0.014)	t value = 1.95 (p = 0.123)
10–19yr	Total	14107 [10072–18142]	5406	13435	t value = −5.99 (p = 0.004)	t value = −0.46 (p = 0.668)
	Epidemic	10943 [6425–15461]	3426	9869	t value = −4.62 (p = 0.010)	t value = −0.66 (p = 0.545)
	Non-epidemic	3164 [2528–3800]	1980	3566	t value = −5.17 (p = 0.007)	t value = 1.75 (p = 0.154)
20–29yr	Total	6410 [4906–7914]	3792	6407	t value = −4.83 (p = 0.008)	t value = −0.01 (p = 0.996)
	Epidemic	4071 [2950–5192]	2194	4516	t value = −4.65 (p = 0.010)	t value = 1.10 (p = 0.332)
	Non-epidemic	2339 [1827–2852]	1598	1891	t value = −4.02 (p = 0.016)	t value = −2.43 (p = 0.072)
30–39yr	Total	9009 [6845–11172]	5109	9492	t value = −5.01 (p = 0.008)	t value = 0.62 (p = 0.569)
	Epidemic	5590 [4073–7107]	2854	6627	t value = −5.01 (p = 0.007)	t value = 1.90 (p = 0.131)
	Non-epidemic	3419 [2609–4229]	2255	2865	t value = −3.99 (p = 0.016)	t value = −1.90 (p = 0.131)
40–49yr	Total	6407 [5144–7669]	3720	7184	t value = −5.91 (p = 0.004)	t value = 1.71 (p = 0.163)
	Epidemic	4035 [2749–5322]	1969	4792	t value = −4.46 (p = 0.011)	t value = 1.63 (p = 0.178)
	Non-epidemic	2371 [2004–2738]	1751	2392	t value = −4.69 (p = 0.009)	t value = 0.16 (p = 0.883)
50–59yr	Total	4522 [3822–5221]	3225	6144	t value = −5.15 (p = 0.007)	t value = 6.44 (p = 0.003)
	Epidemic	2694 [2042–3346]	1671	3897	t value = −4.36 (p = 0.012)	t value = 5.12 (p = 0.007)
	Non-epidemic	1827 [1585–2071]	1554	2247	t value = −3.11 (p = 0.036)	t value = 4.79 (p = 0.009)
≥60yr	Total	4963 [3876–6050]	3349	6494	t value = −4.12 (p = 0.015)	t value = 3.91 (p = 0.174)
	Epidemic	3115 [2220–4009]	1831	4221	t value = −3.98 (p = 0.016)	t value = 3.43 (p = 0.026)
	Non-epidemic	1848 [1608–2088]	1518	2273	t value = −3.82 (p = 0.019)	t value = 4.92 (p = 0.008)

*Total, epidemic, and non-epidemic seasons are weeks 1 to 52, weeks 21 to 44, and weeks 1 to 20 and 45 to 52, respectively.

†Pre-pandemic mean cases from 2004 to 2008, Pandemic cases in 2009, Post-pandemic cases in 2010.

‡Degrees of freedom of all values  =  4.