Table 7.
Arrestin2 multivariate analysis
| Clinical array: Arr2 |
Multivariate analysis |
|||
|---|---|---|---|---|
| Variable | n | HR | P | 95% CI |
| Age at diagnosis | ||||
| <50 | 89 | 1 | – | – |
| ≥50 | 271 | 1.461 | 0.049* | 1.002–2.131 |
| Race | ||||
| Caucasian | 345 | 1 | – | – |
| Other | 15 | 1.400 | 0.309 | 0.732–2.678 |
| Tumor size | ||||
| x<2 cm | 119 | 1 | – | – |
| 2 cm ≤ x < 5 cm | 175 | 1.586 | 0.014* | 1.096–2.294 |
| 5 cm ≤ x | 66 | 2.937 | <0.001*** | 1.927–4.476 |
| Nuclear grade | ||||
| 1 | 54 | 1 | – | – |
| 2 | 201 | 0.928 | 0.741 | 0.598–1.442 |
| 3 | 105 | 1.138 | 0.593 | 0.708–1.828 |
| ER status | ||||
| Negative | 160 | 1 | – | – |
| Positive | 200 | 0.774 | 0.147 | 0.547–1.094 |
| PR status | ||||
| Negative | 176 | 1 | – | – |
| Positive | 184 | 0.985 | 0.926 | 0.713–1.359 |
| Her2 subtype | ||||
| Negative | 334 | 1 | – | – |
| Positive | 26 | 1.457 | 0.230 | 0.788–2.694 |
| Lymph node status | ||||
| Negative | 157 | 1 | – | – |
| Positive | 203 | 1.778 | 0.002** | 1.237–2.554 |
| Arr2 | ||||
| Low | 130 | 1.116 | 0.520 | 0.799–1.559 |
| High | 230 | 1 | – | – |
*
P values <0.05
**
P values <0.01
***
P values <0.001