Table 1.
Properties of the AS1- and AS2-containing peptides used in the study.
| Receptora | GIb | Peptide | Sequence | Net Charge | Hydrophobic moment (μH)c | ΔGwif (kcal/mol)d |
|---|---|---|---|---|---|---|
| Af1503 (278-296) | 1484730 | AS1p-Af1503 | STITRPIIELSNTADKIAE | −1 | 6.28 | −0.71 |
| EnvZEc (180-198) | 947272 | AS1p-EnvZEc | RIQNRPLVDLEHAALQVGK | +1 | 3.84 | −1.51 |
| NarXEc (177-195) | 945788 | AS1p-NarXEc | RLLQPWRQLLAMASAVSHR | +3 | 6.19 | −6.35 |
| TarEc (214-232) | 946399 | AS1p-TarEc | RMLLTPLAKIIAHIREIAG | +2 | 5.79 | −4.32 |
| Af1503 (310-328) | 1484730 | AS2p-Af1503 | DEIGILAKSIERLRRSLKV | +2 | 5.42 | −0.29 |
| EnvZEc (211-229) | 947272 | AS2p-EnvZEc | SEVRSVTRAFNHMAAGVKQ | +2 | 3.46 | −1.51 |
| NarXEc (208-226) | 945788 | AS2p-NarXEc | EMAMLGTALNNMSAELAES | −3 | 5.57 | −2.25 |
| TarEc (246-263) | 946399 | AS2p-TarEc | EMGDLAQSVSHMQRSLTD | −2 | 4.81 | −0.29 |
a
The receptor that served as the source of AS1- and AS2-containing peptides. The position of the residues within the primary structure is provided in parentheses.
b
The “GenInfo Identifier” sequence identification number.
c
The hydrophobic moment (μH) of the peptides according to Eisenberg [58].
d
The energy of interfacial partitioning (ΔGwif) calculated within MPEx [59]. Significantly different values are indicated in bold font.