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. Author manuscript; available in PMC: 2012 May 12.
Published in final edited form as: Cell Immunol. 2011 May 12;270(2):188–197. doi: 10.1016/j.cellimm.2011.05.007

Figure 2.

Figure 2

DC/mBORIS vaccine induces strong antigen-specific cellular responses. (A) mBORIS-specific proliferation of CD4+ T cells detected by CFSE assay. Representative histograms for each group are presented. (B) The activation of IFN-γ producing splenocytes detected by ELISpot analysis. (C) mBORIS-specific humoral immune responses detected by ELISA using pooled sera from 8 mice per group, combined results of two separate measurements. (D) Splenocytes isolated from DC/mBORIS mice killed MHC I-matched 4T1 (H2d), but not unmatched B16 (H2b) target tumor cells.

Data in A, B, and D are representative results from two separate experiments with 8 mice/group in each experiment (bars represent SD: **P<0.01 and ***P<0.001 relative to designated controls).