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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Neuropharmacology. 2011 Jan 26;62(3):1290–1298. doi: 10.1016/j.neuropharm.2011.01.011

Table 4.

Altered expression of placental genes associated with major mental disorders, hypoxia, inflammation, immune response, and apoptosis following infection at E7

Category Downregulated Genes Upregulated Genes
Schizophrenia Egfr, Gria1, Pvr Fyn, Pde10a, Qk, Arhgap18, Robo1, Taf1
Autism Mif, Pik3cg Kdm5a, Pten, Robo1
Bipolar disorder Gria1, Pura Bag1, Fyn
Major depression/Suicide Zfp36 Pten
Hypoxia Atg5, Endog, Edn2, Ero1l, Foxo3, Hes1, Igfbp3, Mif, Smad4, Pigf, Prnp, Tbc1d1, Zfp36 F2r, Fyn, Mnt, Pten, Pdcd2
Inflammation Foxo3, Gpihbp1, Hes1, Mif, Smad4, Prnp, Runx1, Tac4, Zfp36 F2r, Dysf, Fyn, Gng12, Kif5b, Mnt, Pdcd2, Rnasel, Tgtp, Tmem9b
Immune Response Atg5, Ddx3y, Foxo3, Hes1, Igfbp3, Smad4, Msln, Plek2, Pias3, Pus1, Tac4, Zfp36 Dysf, Ebf1, Fyn, Mnt, Pten, Tgtp
Apoptosis Atg5, Csde1, Endog, Foxo3, Git1, Hes1, Igfbp3, Lman1, Mif, Nub1, Ncstn, Prnp, Pias3, Taok1, Zfp36 Acyp1, Atrx, Bcap31, Bag1, Fyn, Lrig2, Magoh, Mnt, Mef2c, Ogt, Pten, Pdcd2, Pa2g4, Qk, Rb1cc1, Stradb, Supv3l1, Suz12, Taf1