Table 1.
Characteristics of Patients Whose Corneal Samples Were Recovered From January Through March 2010
| Characteristic | Group IA |
Group IB |
Group II |
|||
| Fusarium sp | A. flavus | Fusarium sp | A. flavus | Fusarium sp | A. flavus | |
| Age, years | ||||||
| Range | 20–70 | 27–70 | 21–80 | 14–70 | 30–75 | 30–64 |
| Mean (SD) | 46.30 (15.70) | 50.10 (14.02) | 52.77 (14.60) | 50.05 (15.75) | 48.80 (15.10) | 46.30 (10.41) |
| Sex | ||||||
| Male | 17 (73.91) | 12 (57.14) | 12 (54.55) | 11 (57.89) | 5 (50.00) | 7 (70.00) |
| Female | 6 (26.09) | 9 (42.86) | 10 (45.45) | 8 (42.11) | 5 (50.00) | 3 (30.00) |
| Total | 23 (100.00) | 21 (100.00) | 22 (100.00) | 19 (100.00) | 10 (100.00) | 10 (100.00) |
| Size of ulcer, mm2 | ||||||
| <5 | 2 (8.70) | 1 (4.76) | 2 (9.09) | NA | NA | NA |
| 5–10 | 5 (21.74) | 4 (19.05) | 9 (40.91) | 3 (15.79) | NA | NA |
| 10–14 | 10 (43.48) | 8 (38.10) | 4 (18.18) | 9 (47.37) | 1 (10.00) | 2 (20.00) |
| >14 | 6 (26.09) | 8 (38.10) | 7 (31.82) | 7 (36.84) | 9 (90.00) | 8 (80.00) |
| Depth of ulcer | ||||||
| Superficial | 4 (17.39) | 2 (9.52) | 5 (22.73) | 3 (15.79) | NA | NA |
| Mild | 4 (17.39) | 6 (28.57) | 6 (27.27) | 7 (36.84) | 1 (10.00) | 2 (20.00) |
| Deep | 15 (65.22) | 13 (61.90) | 11 (50.00) | 9 (47.37) | 9 (90.00) | 8 (80.00) |
| Hypopyon presence | ||||||
| Yes | 19 (82.61) | 16 (76.19) | 12 (54.55) | 10 (52.63) | 9 (90.00) | 9 (90.00) |
| No | 4 (17.39) | 5 (23.81) | 10 (45.45) | 9 (47.37) | 1 (10.00) | 1 (10.00) |
| Clinical outcome | ||||||
| Healed | 7 (30.43) | 4 (19.05) | 6 (27.27) | 5 (26.32) | NA | NA |
| Treatment failure | 4 (17.39) | 8 (38.10) | 6 (27.27) | 7 (36.84) | 10 (100.00) | 10 (100.00) |
| Lost to follow-up | 12 (52.17) | 10 (47.62) | 10 (45.45) | 7 (36.84) | NA | NA |
NOTE. Data are no. (%) of patients, unless otherwise indicated. Patients (n = 85) in groups IA and IB had corneal ulcers and presented at the clinic within 1–2 weeks after infection; corneal scrapings from the ulcer were used in the present study. Patients (n = 20) in group II had undergone corneal transplants ≥2 weeks after infection, and infected posttransplant corneas were used in the present study. Ten donor corneas from individuals with no infection or inflammation were obtained from the Aravind Hospital’s Eye Bank (mean age, 61 years). A. flavus, Aspergillus flavus; Fusarium sp, Fusarium species; NA, not applicable.