Figure 2.

Contribution of selected USA300 molecules to the formation of rabbit abscesses. A, Average abscess volume for rabbits infected with USA300 (LAC) wild-type or isogenic gene deletion strains as indicated. Results are the mean of 10 abscesses from 5 animals (2 per rabbit). B, USA300 CFUs recovered from rabbit abscesses on day 6 post infection. Each symbol represents data from 1 abscess and the line indicates the mean. C, average abscess volume for rabbits used in B. Data are from rabbit abscess experiments distinct from those shown in A.

For A–C, *P < .05 vs LAC wild-type using a 1-way analysis of variation (ANOVA) and Dunnett test to correct for multiple comparisons. Asterisks in A are matched by color to the appropriate mutant strain. CFUs, colony-forming units.