Figure 1. Resveratrol inhibits cell viability and induces DNA damage selectively in HNSCC cells.
A) Resveratrol effect on cell viability of FaDu, Cal27 and Det562 cells employing MTT assay as detailed in Methods. *; p<0.001 between control and resveratrol; each bar represents mean±SE of three samples from each group. B) and C) Cells were treated for 24 h with indicated concentrations of resveratrol and then comet assay was performed as detailed in Methods. Representative pictures of damaged and undamaged nuclei in HNSCC FaDu, Cal27, Det562 cells (B), and NHEK and HFF cells (C) were captured as detailed in Methods. Res, resveratrol.