Table 1.
Demographics and baseline and change at follow-up measures. Baseline group differences and change at the 2-year follow-up are presented along with the results of a repeated measures ANOVA of Group and Time.
| Nondemented (n=53) | Alzheimer’s Disease (n=37) | Sig. | |||||
|---|---|---|---|---|---|---|---|
| Age at Enrollment | 73.2 (6.7) | 73.8 (5.8) | 0.69 | -- | -- | ||
| Gender (%Female) | 54.7% | 54.1% | 0.95 | -- | -- | ||
| Education (yrs) | 16.6 (2.7) | 15.4 (3.2) | 0.04 | -- | -- | ||
| Baseline | Δ at Follow-up | Baseline | Δ at Follow-up | Group Effect | Time Effect | Group × Time Interaction | |
| Baseline MMSE | 29.5 (0.8) | −0.3 (1.1) | 26.7 (2.6) | −3.1 (5.2) | <0.001 | 0.102 | <0.001 |
| CDR Sum of Boxes | 0 (0) | 0 (0.1) | 2.7 (1.1) | 1.8 (2.7) | <0.001 | 0.042 | <0.001 |
| Global Cognition | 0.2 (0.5) | 0 (0.4) | −1.3 (0.9) | −0.6 (0.7) | <0.001 | 0.142 | <0.001 |
| Peak Oxygen Consumption, VO2 peak (ml*kg−1*min−1) | 23 (6.2) | −1.8 (2) | 20.6 (3.6) | −2.4 (2.1) | 0.003 | 0.831 | 0.214 |