Skip to main content
. 2011 Aug 7;2:435–442. doi: 10.7150/jca.2.435

Table 2.

Synergistic Effect of Erlotinib and Gemcitabine in Cell Lines with Intrinsic Erlotinib Resistance

Combination Indices
Cell Line ED50 ED75 ED90 Dm
Mixture BT-549 0.39275 0.26629 0.18403 6.89283
MDA-MB-468 0.81612 0.70875 0.65044 2.88089
MDA-MB-231 0.70510 0.55634 0.45635 2.42506
Erlotinib BT-549 23.59856
(µM) MDA-MB-468 8.90787
MDA-MB-231 25.7763
Gemcitabine BT-549 342.3832
(nM) MDA-MB-468 29.2352
MDA-MB-231 10.3228