Figure 2.

Severity of GN in WT, Id3^−/−, ApoE^−/−, and DKO female mice at the ages of 16 weeks (A) and 24 weeks (B). H&E-stained kidney sections were evaluated for renal pathological features, as described in Materials and Methods. Each data point represents one mouse. *P = 0.022; ***P < 0.0001 compared with WT. nd, not determined.