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NE1 and NE3 cells expressing various levels of Pea3 and their sensitivity to doxorubicin treatment. A: Western blot analyses were used to detect Flag-Pea3 overexpression. B: Representative histograms of PI-stained cells under different conditions. C: A bar chart showing the percentage of cells in various phases of the cell cycle. Mean ± SD values were obtained from three independent experiments. *P < 0.05 and **P < 0.01 compared with the Scr/empty vector control.
